Alzheimer’s Disease- a form of dementia affecting 5.6 million
Americans, currently incurable – is preventable, according to The Lancet
Neurology, an established medical journal for brain research.
Dr. David Perlmutter, noted board-certified neurologist and expert on
nutrition, is the author of the best-selling book, ‘Grain Brain: The
Surprising Truth about Wheat, Carbs, and Sugar – Your Brain’s Silent
Killer.’ In the book, he states: ‘Lifestyle choices, like aerobic
exercise, healthy fats, reducing carbs, including whole grains, affect
overall brain health, as well as the risk of Alzheimer’s.’ Further, says
Dr Perlmutter, a hi-carb diet, of which 20% comes from wheat-based
food, ‘can lead to Dementia, ADHD, Anxiety, Chronic Headaches,
Depression and other neurological diseases.
Gluten in wheat leads to gluten sensitivity and the production of
Zonulin in the gut, according to Dr. Dasano, a pediatric
gastroenterologist and research scientist directing the Center for
Celiac Research & Treatment at Mass, General Hospital, Boston.
Zonulin is the cornerstone of diseases characterized by the permeability
of the gut and inflammation in the brain – Alzheimer’s, Autism,
Parkinson’s, and Attention Deficit Disorders as well as auto-immune
diseases’- related to consumption of carbohydrates, says Dr. Perlmutter.
Dr. Fasano’s research shows that reaction to Zonulin is not confined to
the 1.85% with Celiac, but is present in 100% of the population.
According to a recent German study at the University of Bonn,
published in Neurology, a hi-carb diet has been directly related to
atrophy, or brain shrinkage, particularly of the memory center. A blood
test for hemoglobin, A1C, which assesses average blood sugar, is used to
correlate blood sugar level to disease processes, such as Alzheimer’s,
mild cognitive impairment and Coronary Heart Disease. Researchers
concluded that elevated hemoglobin A1C is directly correlated with brain
shrinkage, including the brain memory structure, the hippocampus.
Dr Perlmutter, in his book, ‘Grain Brain’, recommends aerobic
exercises, plus a diet rich in vitamin D, good gats’, such as coconut,
sesame and nut oil, flaxseed oil – the brain is 60-70% fat, and
maintained by fats consumption – rich in above-ground vegetables, and
aggressively low in carbohydrates (60 gm/day).
A switch to such a healthy diet and lifestyle can, says Dr.
Perlmutter, effect neurogenesis, whereby we can have some control, or
programming of our genes, and neuroplasticity, renewing brain function.
Studies show that as a result, our memory centers can expand at 1-2% per
year, and increase the connection of brain cells. He says that this
dietary approach can also apply to Heart Disease and Cancer.
‘Grain Brain’, clearly emphasizes the restriction of gluten, wheat and carbohydrates, and its impact on brain health.
– Dr. Perlmutter.com, Dr. Joseph Mercola’s interview of Dr. Perlmutter, 2013, PBS Grain Brain Series.